| 摘要 |
<p>An organism which does not express its natural nisA gene product, but is capable of expressing genes for nisin modification, immunity and translocation out of the cell is produced. The organism may be transformed with a coding sequence for a variant prenisin and, if necessary, appropriate regulatory sequences for expression thereof such that the organism is capable of secreting the corresponding variant nisin. A process for exclusively producing a variant nisin therefore comprises fermenting this organism and obtaining the nisin so produced.</p> |
