| 摘要 |
PCT No. PCT/SE93/00272 Sec. 371 Date Dec. 23, 1994 Sec. 102(e) Date Dec. 23, 1994 PCT Filed Mar. 31, 1993 PCT Pub. No. WO93/19756 PCT Pub. Date Oct. 14, 1993Quinoline-3-carboxamide compounds of formula (I) are effective in preventing, treating or ameliorating Type I diabetes. <IMAGE> wherein ----- represents two conjugated double bonds between the atoms comprised by the dashed line, X1 and X2 are independently selected from an oxygen atom or NH9, H1-9 independently represent a hydrogen atom or a substituent, wherein H7 and H8 are attached to different atoms selected from X1, X2 and the ring nitrogen atom of the quinoline ring. In particular, X1 and X2 being bound by a single bond to the ring when H7 or H8 is bonded thereto and by a double bond when H7 or H8 is not bonded thereto. |
