| 摘要 |
Compounds of formula (I) <IMAGE> (I) in which R1 is A-N(O)R'R'' and R2, R3 and R4 are each separately selected from hydrogen, X and NH-A-N(O)R'R'' wherein X is hydroxy, halogeno, amino, C1-4 alkoxy or C2-18 alkanoyloxy, A is a C2-4 alkylene group with a chain length between N or NH and N(O)R'R'' of at least 2 carbon atoms and R' and R'' are each separately selected from C1-4 alkyl groups and C2-4 hydroxyalkyl and C3-4 dihydroxyalkyl groups in which the carbon atom attached to the nitrogen atom does not carry a hydroxy group and no carbon atom is substituted by two hydroxy groups, or R' and R'' together are a C2-6 alkylene group which with the nitrogen atom to which R' and R'' are attached forms a heterocyclic group having 3 to 7 atoms in the ring, and physiologically acceptable salts thereof are of value in the treatment of anaerobic bacterial infections. |
