PROCESS FOR PREPARING OPTICALLY ACTIVE ALPHA-HYDROXY-CARBOXYLIC ACIDS

摘要

The invention relates to a process for the preparation of optically active alpha -hydroxycarboxylic acids characterised in that carbamates are first reacted in the presence of a selective base and of a chelate-forming diamine to give a carbanion complex compound, this is then dia- or enantioselectively deprotonated, then substituted with CO2 and, as a final step, the heterocyclic protective group is eliminated.