Abrasion resistant stopper to prevent generation of particles by piercing.

摘要

An abrasion-resistant stopper (10) for a medical vial for containing a fluid therein comprising a stopper body of an elastomeric material having a head portion (20) and a fluid contactable leg portion (30), the leg portion (30) being adapted to be inserted into the medical vial for hermetically sealing the fluid therein and the head portion (20) comprising a top surface to receive a coating thereon, the top surface being coated with an abrasion-resistant coating (40) to prevent generation of particles upon piercing of the stopper (10) by a spike or a hypodermic needle. Preferably the coating (40) covers at least the centre, pierceable portion of the top surface and is advantageously polytetrafluoroethylene. <IMAGE>