| 摘要 |
A piperidine compound of the formula (I): <IMAGE> wherein A is a fused aromatic ring; R is hydrogen, chloro or methoxy; X is (CH2)n, which may be substituted, in which n is 0 or an integer of 1 to 10, -CH=CH-, -C=C-, -O-, -S-, -NH-, -N(COCH3)-, -N(COOC2H5)-, -N(CHO)-, -N(CH3)-, -CO-, -SO-, or -SO2-; Y is -CH=CH-, -CH2CH2-, -CH2CO-, -O-, -S-, -NH-, -OCH2-, -SCH2-, -NHCH2-, -CH(OH)CH2- or -CH(OH)CH(OH)-; and Q is substituted or unsubstituted n-hexyl, carboxypropyl, ethoxycarbonylpropyl, cyanopropyl, cyclohexyl, phenyl, indanyl, naphthyl, tetrahydronaphthyl, benzocycloheptyl, piperidinyl, tetrahydroisoquinolinyl, indolyl, pyrolyl, furyl, thienyl, thiazolyl, oxazolyl or N-methylpyrolyl, wherein any one or more of the -(CH2)-groups of the hexyl, carboxypropyl, ethoxycarbonylpropyl and cyanopropyl groups may be replaced by -CH=CH-, -C=C-, -O-, -S-, -NH-, -N(COCH3), -N(COC2H5)-, -N(CHO)-, -N(CH3)-, -CO-, -SO- or -SO2-, and wherein one or more of the -(CH2)-groups in X and Q may be substituted by -(CH2)4- or -(CH2)5- thereby forming a ring structure.
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