发明名称 Ketamine analogues for treatment of thrombocytopenia
摘要 5,6-Dehydronorketamine and derivatives retaining the alpha , beta -unsaturated carbonyl are disclosed. These and other Michael or Michael-type acceptors and adducts are shown to influence the replication, differentiation or maturation of blood cells, especially platelet progenitor cells. Accordingly, these compounds are used for treatment of thrombocytopenia.
申请公布号 US5250732(A) 申请公布日期 1993.10.05
申请号 US19910732365 申请日期 1991.07.18
申请人 GENENTECH, INC. 发明人 KOGAN, TIMOTHY P.;SOMERS, TODD C.
分类号 C07C225/20;C07C237/06;C07C323/60;C07D495/04;(IPC1-7):C07C233/06;C07C237/18 主分类号 C07C225/20
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