摘要 |
FIELD: chemical industry and pharmaceutical industry. SUBSTANCE: present invention describes amino acid derivatives of formula I: <EMI ID=0.347 HE=27 WI=36 TI=CHI> wherein R is C<SB>1</SB>-C<SB>8</SB> alkoxycarbonyl or group of formula: <EMI ID=0.348 HE=18 WI=18 TI=CHI> wherein R is C<SB>1</SB>-C<SB>8</SB> alkyl; R is hydrogen, and R is hydroxy group or R and R in combination are oxo group; R is C<SB>1</SB>-C<SB>8</SB> alkoxycarbonyl or C<SB>1</SB>-C<SB>8</SB>-alkylcarbamoyl; R and R in combination are trimethylene or tetramethylene; R is phenyl-C<SB>1</SB>-C<SB>8</SB> alkoxycarbonyl, quinolylcarbonyl; R is C<SB>1</SB>-C<SB>8</SB> alkyl, phenyl-C<SB>1</SB>-C<SB>8</SB> alkyl, cyano-C<SB>1</SB>-C<SB>8</SB> alkyl, carbamoyl-C<SB>1</SB>-C<SB>8</SB> alkyl, C<SB>1</SB>-C<SB>8</SB>-alkyltyl-C<SB>1</SB>-C<SB>8</SB> alkyl, carbamoyl-C<SB>1</SB>-C<SB>8</SB> alkyl or pharmaceutically acceptable basic salts thereof and are used for prophylaxis or treatment of viral infections. They are prepared by well known methods. EFFECT: improved properties of the pharmaceutical composition. 19 cl, 1 tbly |