发明名称 Amino acid derivatives
摘要 FIELD: chemical industry and pharmaceutical industry. SUBSTANCE: present invention describes amino acid derivatives of formula I: <EMI ID=0.347 HE=27 WI=36 TI=CHI> wherein R is C<SB>1</SB>-C<SB>8</SB> alkoxycarbonyl or group of formula: <EMI ID=0.348 HE=18 WI=18 TI=CHI> wherein R is C<SB>1</SB>-C<SB>8</SB> alkyl; R is hydrogen, and R is hydroxy group or R and R in combination are oxo group; R is C<SB>1</SB>-C<SB>8</SB> alkoxycarbonyl or C<SB>1</SB>-C<SB>8</SB>-alkylcarbamoyl; R and R in combination are trimethylene or tetramethylene; R is phenyl-C<SB>1</SB>-C<SB>8</SB> alkoxycarbonyl, quinolylcarbonyl; R is C<SB>1</SB>-C<SB>8</SB> alkyl, phenyl-C<SB>1</SB>-C<SB>8</SB> alkyl, cyano-C<SB>1</SB>-C<SB>8</SB> alkyl, carbamoyl-C<SB>1</SB>-C<SB>8</SB> alkyl, C<SB>1</SB>-C<SB>8</SB>-alkyltyl-C<SB>1</SB>-C<SB>8</SB> alkyl, carbamoyl-C<SB>1</SB>-C<SB>8</SB> alkyl or pharmaceutically acceptable basic salts thereof and are used for prophylaxis or treatment of viral infections. They are prepared by well known methods. EFFECT: improved properties of the pharmaceutical composition. 19 cl, 1 tbly
申请公布号 ZA9203184(B) 申请公布日期 1993.10.04
申请号 ZA19920003184 申请日期 1992.04.30
申请人 F. HOFFMANN-LA ROCHE A.G. 发明人 JOSEPH ARMSTRONG MARTIN;GARETH JOHN THOMAS
分类号 C07C271/20;A61K;A61K31/13;A61K31/164;A61P31/12;C07C;C07C237/06;C07D263/04 主分类号 C07C271/20
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