The wrist-stabilization system includes an inflatable bladder (12) having a plurality of channels (52) in intercommunication one with the other and an inlet (68) for inflating the channels (52). A glove (10) or a wristband positions the bladder on a user's upper extremity such that substantially equal portions of the channels lie above and below the wrist joint to inhibit wrist joint motion in flexion and extension and assist in maintaining the lateral sides of the hand and forearm in the lateral plane. A manually actuatable inflation/deflation device (14) is secured to the glove, wristband or bladder and coupled to the bladder whereby the bladder can be manually inflated and deflated.