Kosmetische und pharmazeutische Mittel zur Behandlung der Haut

摘要

Skin anti-wrinkle compositions comprise cosmetic creams, lotions, sprays, and beauty preparations containing 0.01-1% of an elastolytic enzyme isolated from defatted pancreas powder. Depolymerisation of elastine, the complex mucoproteins of the skin, preventing the accompanying wrinkling which occurs with ageing. Useful in various types of skin beauty preparations particularly for women. Pancreas is defatted with acetone and ether and the dry powder is purified by precipitation with 48-55% (NH4)2SO4. After dialysis the product is further purified by precipitation with ethanol. Finally, after solution in M/100 pH 4.7-5.0 acetate buffer, the solution is lyophilised to give the stable enzyme.