摘要 |
PCT No. PCT/EP90/00432 Sec. 371 Date Sep. 19, 1991 Sec. 102(e) Date Sep. 19, 1991 PCT Filed Mar. 14, 1990 PCT Pub. No. WO90/12015 PCT Pub. Date Oct. 18, 1990. <IMAGE> (I) Platelet activating factor antagonists of formula (I), in which R2 is optionally substituted phenyl, R1 is H, alkyl or arylalkyl, Het is an optionally substituted N-containing heterocyclic group optionally fused to a phenyl or a further heterocyclic ring, and Z completes an optionally substituted carbocyclic or heterocyclic ring having a carbonyl group attached to the 5-position of the dihydropyridine ring. The compounds are useful for treating allergic and inflammatory conditions.
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