Halichondrin derivatives, isolatable from a marine sponge of the Lissodendyx Sp., have cytotoxic preparations and are of the formula: in which R1 and R2 together represent a group of the formula: or .
申请公布号
CA2092108(A1)
申请公布日期
1993.09.24
申请号
CA19932092108
申请日期
1993.03.22
申请人
GRAVALOS, DOLORES G.;LAKE, ROBIN J.;BLUNT, JOHN W.;MUNRO, MURRAY H. G.;LITAUDON, MARC S. P.;LITAUDON, MARC S. P.
发明人
GRAVALOS, DOLORES G.;LAKE, ROBIN J.;BLUNT, JOHN W.;MUNRO, MURRAY H. G.;LITAUDON, MARC S. P.
