发明名称 |
Blood substitutes comprising recombinant hemoglobin. |
摘要 |
<p>Solutions of mutant hemoglobins having a lower oxygen affinity than that of native hemoglobin are used as blood substitutes. The mutant hemoglobins are preferably obtained by recombinant DNA techniques. Both alpha and beta globin chains can now be so prepared, making possible the production of wholly artificial hemoglobin, whether conventional or mutant in form. Solutions of wholly artificial hemoglobins are also used as blood substitutes.</p> |
申请公布号 |
EP0561245(A1) |
申请公布日期 |
1993.09.22 |
申请号 |
EP19930103633 |
申请日期 |
1988.05.13 |
申请人 |
SOMATOGENETICS INTERNATIONAL, INC.;MEDICAL RESEARCH COUNCIL |
发明人 |
HOFFMAN, STEPHEN J.;NAGAI, KIYOSHI |
分类号 |
A61K38/00;C07K14/805 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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