发明名称 |
Method of assessing reperfusion after thrombolytic therapy |
摘要 |
The present invention is a method of diagnosing the presence of a persistent occlusion in a myocardial infarct patient undergoing thrombolytic therapy. The method comprises detecting a series of three variables from the patient and then generating the probability of the presence of a persistent occlusion from those variables. The first variable comprises a serum creatine kinase MB (CK-MB) level from a patient at the onset of thrombolytic therapy. The second variable comprises a second CK-MB level in the patient at a predetermined time after the onset of thrombolytic therapy. The third variable comprises the presence or absence of chest pain a predetermined time after the onset of thrombolytic therapy. In a preferred embodiment of the present invention, the second and third variables are detected within 30 minutes of each other and within about 1 to about 3 hours after the initial variable is detected. In an alternate embodiment a fourth variable reflecting the time from onset of chest pain to the beginning of thrombolytic therapy is included in the regression model.
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申请公布号 |
US5246001(A) |
申请公布日期 |
1993.09.21 |
申请号 |
US19920860856 |
申请日期 |
1992.03.31 |
申请人 |
DUKE UNIVERSITY |
发明人 |
OHMAN, MAGNUS E.;CHRISTENSON, ROBERT H.;CALIFF, ROBERT M.;SIGMON, KRISTINA N. |
分类号 |
G06F19/00 |
主分类号 |
G06F19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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