6-alpha methyl-17 alpha-caproyloxy-19-non- - progesterone having progestative and anti-

摘要

The novel title cpd. may be prepd. by (1) reducing 6-formyl-17 alpha-caproyloxy-20-oxo-19-nor-pregna-3,5-diene with palladium and cyclohexene; (2) reducing a 3,20-dioxo-6-methylene-17 alpha-caproyloxy-19-nor-pregn-4-ene with hydrogen and a palladium catalyst; (3) dehydrating a 3,20-dioxo-5 alpha-hydroxy-6-methyl-17 alpha-caproyloxy-19-nor-pregnane with a base or mineral acid or (4) hydrogenating a 6-disubstd. amino 17 alpha-caproyloxy-20-oxo-19-nor-pregna-3,5-diene with hydrogen and a catalyst.