Pharmaceutically useful dibenzofurancarboxamides of specific stereo-configuration
摘要
This invention is directed to certain dibenzofurancarboxamides and their use as 5HT3 antagonists having unique CNS, anti-emetic and gastric prokinctic activity void of any significant D2 receptor binding properties. This invention also describes novel processes necessary for their preparation.
申请公布号
US5246942(A)
申请公布日期
1993.09.21
申请号
US19920887594
申请日期
1992.05.29
申请人
RHONE-POULENC RORER PHARMACEUTICALS INC.
发明人
YOUSSEFYEH, RAYMOND D.;CAMPBELL, HENRY F.;KUHLA, DONALD E.;AIREY, JOHN E.;KLEIN, SCOTT I.;POWERS, MATTHEW R.