Method for inhibiting production of IgE by using IL-9 inhibitors
摘要
A method for inhibiting production of IgE, and a method for enhancing production of IgG are taught. The methods are linked to the role of interleukin 9 in antibody production. Specifically, production of IgG is potentiated by administering either to a subject or a cell culture a combination of interleukin 4 and interleukin 9. Production of IgE is inhibited by administering an amount of an interleukin 9 inhibitor to a subject.
申请公布号
US5246701(A)
申请公布日期
1993.09.21
申请号
US19910807260
申请日期
1991.12.13
申请人
LUDWIG INSTITUTE FOR CANCER RESEARCH;DEPARTMENT D'IMMUNOLOGIE INSTITUT HENRI BEAUFOUR
发明人
DUGAS, BERNARD;DRUEZ, CATHERINE;BRAQUET, PIERRE;MENCIA-HUERTA, JEAN M.;UYTTENHOVE, CATHERINE;RENAULD, JEAN-CHRISTOPHE;VAN SNICK, JACQUES