PRODUCTION OF 2-HALO-3,5-DIFLUOROANILINE, INTERMEDIATE FOR PRODUCING THE SAME, AND PRODUCTION OF SAID INTERMEDIATE

摘要

A process for producing 2-halo-3,5-difluoroaniline by heating 4-amino-5-halo-2,6-difluoroisophthalonitrile in the presence of sulfuric acid with a concentration of 50 wt.% or above at a temperature ranging from 80 DEG C to the boiling point of the reaction mixture; 4-amino-5-halo-2,6-difluoroisophthalamide as an intermediate for the production of the aniline; and a process for producing the amide. The above aniline and amide are useful as the starting material or intermediate for producing pharmaceutical, agricultural and industrial chemicals.