2-AMINOSUGAR DERIVATIVES OF MACROLIDES

摘要

Macrolides of formula (I) and methods of treatment of resistance to transplantation, fungal infections and autoimmune diseases such as rheumatoid arthritis and psoriasis using said macrolides of formula (I), wherein n is 1 or 2; A and B are taken together and form =O or A and B are taken separately and are each H or A is OH and B is H; R<1> is a 2-aminoglycosyl group; R<2> is OH or a glycosyloxy group; and R<3> is an alkyl or allyl group.