| 摘要 |
An inclusion complex comprising (1) the pharmaceutical agent Propofol (2,6-bis(methylethyl)phenol) of Alfaxalone, i.e., 3-hydroxypregnane-11,20-dione, and (2) a cyclodextrin derivative comprising an otherwise substituted or unsubstituted cyclodextrin in which at least one C2, C3 or C6 hydroxyl is substituted with a group selected from -XR<1>, -YR<2>R<3>, -SiR<4>R<5>R<6>, and -R<7>, wherein X can represent (a), (b), (c), Y can represent (d), (e), (f), (g). |
| 申请人 |
AUSTRALIAN COMMERICAL RESEARCH & DEVELOPMENT LIMIT |
发明人 |
PALMER, CLIVE, FREDERICK;HO, PAUL, CHI, CUI;BROWN, SUSAN, ELISABETH,;MAY, BRUCE, LINDLEY;SCHIESSER, DEBORAH, SUSANNE;LUO, YIN;DENNIS, NICHOLAS;LINCOLN, STEPHEN, FREDERICK;COATES, JOHN, HEWLETT;EASTON, CHRISTOPHER, JOHN;DUCKWORTH, PAUL;WANG, PENG;COGHLAN, DANIEL, R.,;JANOWSKI, WIT;LEPORE, ANGELO;WILLIAMS, MICHAEL, LLOYD;VAN EYK, STEVEN, JOHN, |
