发明名称 |
ASSAY FOR ADRENAL AUTOANTIGEN |
摘要 |
Adrenal autoantigen is isolated and characterised as a protein obtainable from the microsome fraction of the adrenal gland, having a molecular weight of about 50,000 to 60,000 and antigenic towards adrenal autoantibody. The protein innative, recombinant or modified form as well as fragments thereof comprising an epitope for adrenal autoantibody are used in a method and kit for detecting adrenal autoantibodies. The protein is also useful as a medicament for treating Addisson's disease. Absorption studies show that the autoantigen is steroid 21-hydroxylase. |
申请公布号 |
WO9318406(A1) |
申请公布日期 |
1993.09.16 |
申请号 |
WO1993GB00443 |
申请日期 |
1993.03.04 |
申请人 |
RSR LIMITED |
发明人 |
FURMANIAK-WEHR, JADWIGA, MARIA |
分类号 |
G01N33/53;A61K35/14;A61K38/00;C12N1/19;C12N5/08;C12N9/02;C12N15/00;C12R1/865;G01N33/564 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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