发明名称 |
DESOSAMINO DERIVATIVES OF MACROLIDES AS IMMUNOSUPPRESSANTS AND ANTIFUNGAL AGENTS |
摘要 |
Macrolides of formula (I) and methods of treatment of resistance to transplantation, fungal infections and autoimmune diseases such as rheumatoid arthritis and psoriasis using said macrolides of formula (I), wherein n is 1 or 2; A and B are taken together and form =O or A and B are taken separately and are each H or A is OH and B is H; R<1> is a desosamino group; R<2> is OH or a desosaminyloxy group; and R<3> is an alkyl or allyl group. |
申请公布号 |
WO9318042(A1) |
申请公布日期 |
1993.09.16 |
申请号 |
WO1993US00426 |
申请日期 |
1993.01.27 |
申请人 |
PFIZER INC. |
发明人 |
HAUSKE, JAMES, R.;SCHULTE, GARY, R. |
分类号 |
A61K31/40;A61K31/435;A61P31/04;A61P31/10;A61P37/06;C07D498/18;C07H19/01 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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