发明名称 |
VERFAHREN ZUR HERSTELLUNG VON SUBSTITUIERTEN INDOLINONDERIVATEN. |
摘要 |
A process which comprises reductive cyclisation of a compound of structure (II) <CHEM> in which n is 1 to 3 and X is a group displaceable by amine in the presence of at least two equivalents of anhydrous iron (III) chloride and at least two equivalents of an acetyl halide and a solvent to form a compound of structure (III) <CHEM> in which X and n are as hereinabove defined, Z is halogen. f |
申请公布号 |
AT93521(T) |
申请公布日期 |
1993.09.15 |
申请号 |
AT19880305510T |
申请日期 |
1988.06.16 |
申请人 |
SMITH KLINE & FRENCH LABORATORIES LIMITED |
发明人 |
FORTUNAK, JOSEPH M.;POWDER MILLS,;GILES, ROBERT GORDON;POWDER MILLS,;WALSGROVE, TIMOTHY CHARLES;OLD POWDER MILLS, |
分类号 |
A61K31/40;C07C45/60;C07C45/85;C07C47/55;C07C67/00;C07C201/00;C07C205/00;C07C205/09;C07D209/34 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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