ANALOGUES OF KIOTORPHINE AND METHOD FOR THEIR PREPARATION

摘要

These compounds find application as neuromodulators in medicine. They have the following general formula:<IMAGE>where X is Cl or Br. The method involves reacting the compounds<IMAGE>or<IMAGE>with unprotected canavanine in a medium of dimethylformamide and triethylamine, respectively NaHCO3 and NaOH, at room temperature for 16-36 hours.