| 发明名称 |
DERIVATIVES OF PHYSIOLOGICALLY ACTIVE SUBSTANCE ML-236B AND PROCESS FOR PRODUCTION THEREOF |
| 摘要 |
PCT No. PCT/JP89/00201 Sec. 371 Date Oct. 3, 1989 Sec. 102(e) Date Oct. 3, 1989 PCT Filed Feb. 28, 1989 PCT Pub. No. WO89/08094 PCT Pub. Date Sep. 8, 1989.A compound represented by the following general formula: <IMAGE> wherein R1 and R2 are the same or different, and represent a hydrogen or halogen, and ring-opened free acid, amides and salts thereof are provided. The present invention also provides a process for the production of the above-mentioned compound starting from the known compound ML-236B.
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| 申请公布号 |
US5245050(A) |
申请公布日期 |
1993.09.14 |
| 申请号 |
US19890427085 |
申请日期 |
1989.02.28 |
| 申请人 |
TOBISHI YAKUHIN KOGYO KABUSHIKI KAISHA |
发明人 |
ENDO, AKIRA;TOSHIOKA, TADASHI;UMEZAWA, ISAO;YUASA, MASAYUKI;INABA, TAKASHI;INOUE, TSUTOMU |
| 分类号 |
A61K31/22;A61K31/365;A61K31/366;A61P3/06;C07C67/293;C07C67/313;C07C69/00;C07C69/24;C07D309/30 |
主分类号 |
A61K31/22 |
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