发明名称 Pharmaceutical compositions and their use for treating zinc deficient disorders
摘要 A zinc depot for animals may be established through the introduction of a zinc substance exhibiting slow-release characteristics for the physiology of the animal, preferably via a non-digestive route. A fluid or paste-like composition, or a bolus, may be introduced through preferred routes such as into the bloodstream, intramuscularly, or subcutaneously. Preferred zinc substances include zinc organic salts and a specified range of preferred zinc inorganic compounds. Most exhibit a low aqueous solubility, less than or equal to 0.01 g/ml of H2O at 35 DEG C. Other agents may enhance the effectiveness of the zinc substance, preferred agents including calcium, magnesium or selenium containing compounds or minerals, fatty acids, vegetable oils, and/or sulphur or sulphide compounds. The provision of a lasting zinc depot in an animal is useful for addressing zinc responsive disorders, both in a preventative and remedial sense. Examples of zinc-responsive disorders include facial eczema, fading elk's disease, mycotoxin poisoning, poisoning from alkaloid substances, disorders relating to phyto-oestrogen levels, and zinc deficiencies.
申请公布号 AU3649893(A) 申请公布日期 1993.09.13
申请号 AU19930036498 申请日期 1993.02.17
申请人 COLBY CORPORATION LIMITED 发明人 ROBERT JAMES PICKERING
分类号 A61K31/30 主分类号 A61K31/30
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