发明名称 |
EXPRESSION OF HIGHER EUCARYOTIC GENES IN -I(ASPERGILLUS) |
摘要 |
<p>A method for expressing higher eucaryotic genes in Aspergillus through the use of a recombinant plasmid capable of integration into the chromosomal DNA of Aspergillus is disclosed. It is preferred to utilize a transcriptional promoter within a DNA construct contained in the plasmid that is of a DNA sequence encoding an ADH enzyme or a TPI enzyme. Promoters capable of directing the expression of a heterologous gene in Aspergillus, as well as other filamentous fungal genera are also disclosed.</p> |
申请公布号 |
EP0272277(B1) |
申请公布日期 |
1993.09.08 |
申请号 |
EP19870901195 |
申请日期 |
1987.01.15 |
申请人 |
ZYMOGENETICS, INC. |
发明人 |
MCKNIGHT, GARY, L.;UPSHALL, ALAN |
分类号 |
C07K14/535;C07K16/00;C12N9/04;C12N9/34;C12N9/72;C12N9/90;C12N15/80 |
主分类号 |
C07K14/535 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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