发明名称 Peptide boronic acid inhibitors of trypsin-like proteases
摘要 Peptides comprising C-terminal boronic acid derivatives of lysine, ornithine, and arginine, homoarginine and corresponding isothiouronium analogs thereof, are reversible inhibitors of trypsin-like serine proteases such as thrombin, plasma kallikrein and plasmin.
申请公布号 US5242904(A) 申请公布日期 1993.09.07
申请号 US19920848296 申请日期 1992.03.09
申请人 THE DUPONT MERCK PHARMACEUTICAL COMPANY 发明人 KETTNER, CHARLES A.;SHENVI, ASHOKKUMAR B.
分类号 C07F5/02;C07K5/00 主分类号 C07F5/02
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