摘要 |
The present invention provides novel phenylacetamide derivatives having the following formula <IMAGE> wherein: X is a hydrogen, halogen, hydroxy, nitro, amino, R1, NR1R2, NHR1 or OR1 wherein R1 and R2 are an optionally substituted C1-8 alkyl, cycloalkyl or benzyl group, respectively; Y, which may be the same or different when p is greater than 1, is a hydrogen, halogen, methylenedioxy, hydroxy, trifluoromethyl, R3 or OR3 wherein R3 is an optionally substituted C1-8 alkyl or benzyl group; n is an integer from 1 to 6; and p is an integer from 1 to 5; and pharmaceutically acceptable salts thereof which have powerful analgesic and anti-inflammatory activities. The invention also provides processes for preparing these compounds and pharmaceutical compositions containing them as an active ingredient.
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申请人 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY |
发明人 |
PARK, NO S.;HA, DEOK C.;CHOI, JOONG K.;KIM, HYUN S.;HONG, MI S.;LIM, HEE J.;LEE, KWANG S. |