| 摘要 |
<p>A novel glycosylated form of albumin, designated EGA, is further characterized by its cell growth promoting activity. A process of isolation of human or bovine glycosylated albumin is described. The EGA fractions have been identified by serological histochemical and biological assays as well as lectin reactivity. The growth-promoting effect of EGA is directed to various transformed cell lines and primary cells of mammalian origin. Also described is a neutralizing antibody to the EGA of the present invention produced from a parental cell line. Novel compositions of EGA containing media are provided for cell, tissue or organ culture and diagnostic and therapeutic procedures are provided. Further, hybridoma cell lines producing inhibiting or neutralizing antibodies or antibodies or antibodies against EGA are described.</p> |
