| 摘要 |
Compounds of formula (I) in which R1 represents hydrogen, a C1-6 aliphatic h ydrocarbyl group or a C1-4 aliphatic hydrocarbyl group substituted by a C3-6 alicyclic hydrocarbyl group or by a phenyl group, which phenyl group is unsubstituted or substituted by a halogeno or C1-3 halogenoalkyl group, R2 represents hydr ogen, R3 represents hydrogen, a 5- or 6-membered ring aromatic heterocyclyl group containing one or two heteroatoms selected from nitrogen, oxygen and sulphur which is unsubstituted or substituted by a halogeno or C1-3 halogenoalkyl gr oup, or a group AR wherein A is a straight chain C1-4 aliphatic hydrocarbyl group terminally substituted by R which is hydrogen, a phenyl group or a 5- or 6-membered ring aromatic heterocyclyl group containing one or two heteroatoms selected from nitrogen, oxygen and sulphur, which phenyl or heterocyclyl group R is unsubstituted or substituted by a ha logeno or C1-3 halogenalkyl group, R4 and R5 each represent hydrogen or together represent an oxo group and R6, R7 and R8 each represent hydrogen, or R4 represents hydrogen and two of R5, R6, R7 and R8 together represent the second bond of a double bond joining positions 4 and 5, 5 and 6 or 6 and 7 with the remaining two of R5, R6, R7 and R8 representing hy drogen, the compound optionally being in the form of a salt thereof formed with a physiologically acceptable inorganic or organic acid, are of value for the treatment of anxiety and in the improvement of learning ability and/or the reversal of am nesia.
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