摘要 |
PCT No. PCT/AU90/00183 Sec. 371 Date Dec. 27, 1991 Sec. 102(e) Date Dec. 27, 1991 PCT Filed May 7, 1990 PCT Pub. No. WO90/13299 PCT Pub. Date Nov. 15, 1990.The present invention relates to a method of enhancing implantation of an embryo within the uterus of a female mammal. The method comprises administering an amount of a PAF antagonist, effective to enhance implantation, to the mammal. The invention also relates to a method of increasing the level of PAF around an embryo in the uterus of a female mammal by administering an amount of a PAF antagonist sufficient to inhibit PAF catabolism. Desirably the PAF antagonist is administered together with PAF or a homologue or analogue thereof. The invention also provides compositions comprising a PAF antagonist together with PAF or a homologue or analogue thereof, and a process for preparing the same.
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