| 摘要 |
<p>Title cpds. of formula (I) (where R1 is H or 1-3C alkyl; R2 is H, halogen or 1-3C alkyl, alkoxy or alkylthio; R3 is halogen, H, 1-3C alkyl or alkoxy or OH, and A is di- or trimethylene in which 1H atom can be replaced by OH or 1-3C alkyl) which are partic. useful for treating essential and renal hypertension, are prepd. by reacting a cpd. of formula (IIIe (where R4 is SR5, OR5 or NHNO2 and R5 is H or 1-3C alkyl) or its acid addn. salt with H2N-A-NH2 (III) or its mono- acid addn. salt, cyclising a cpd. of formula (V) or reacting a cpd. of formula (VI) with (III) or its mono-acid addn. salt.</p> |
