发明名称 HEPATOMA TREATMENT WITH SOMATOSTATIN ANALOGS
摘要 2107773 9316718 PCTABS00025 A method for treating liver cancer in a mammalian subject. The method includes administering to the subject a composition which contains a therapeutically effective amount of an octapeptide of the following formula: H-A1-Cys-A2-D-Trp-Lys-A3-Cys-A4-Y wherein, A1 is D-.beta.-Nal or D-Phe; A2 is Phe, pentafluro-Phe, or p-substituted X-Phe where X is a halogen, NH2, NO2, OH, or C1-3 alkyl; A3 is Thr, Ser, Phe, Val, .alpha.-aminobutyric acid, or Ile; A4 is Thr, $(b)-Nal, or Trp; and Y is NH2 or OH; or a pharmaceutically acceptable salt of complex thereof.
申请公布号 CA2107773(A1) 申请公布日期 1993.08.26
申请号 CA19932107773 申请日期 1993.02.25
申请人 BIOMEASURE, INC. 发明人 BOGDEN, ARTHUR E.
分类号 A61K38/04;A61K38/00;A61K38/31;A61P1/16;A61P35/00;C07K7/06;C07K14/575;C07K14/655;(IPC1-7):A61K38/31 主分类号 A61K38/04
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