摘要 |
Arylhydroxamates are provided having the structure <IMAGE> wherein R1 is hydrogen, lower alkyl, aryl, lower alkenyl, cycloalkenyl, aralkyl, or <IMAGE> wherein n is 1 to 4 and X is hydroxy, alkoxy, amino, C1-C4-alkylamino or C1-C4-dialkylamino. R2 is hydrogen or lower alkyl; and R3 is C1-C20 alkyl or C3-C20 alkenyl, aryl, aryl-alkyl, cycloalkyl, aryl-alkenyl, lower alkoxy, lower alkenyloxy, aryl-alkoxy or cycloalkyloxy. These compound are useful as inhibitors of DELTA 5-lipoxygenase and as such are useful as antiallergy agents. |
申请人 |
E.R. SQUIBB & SONS, INC., PRINCETON, N.J., US |
发明人 |
KARANEWSKY, DONALD S., EAST WINDSOR NEW JERSEY, US;HASLANGER, MARTIN F., LAMBERTVILLE NEW JERSEY, US |