发明名称 A DOSAGE FORM COMPRISING AN ANTIGEN AND A MULTILAMELLAR LIPOSOME COMPRISING DIMYRISTOLYPHOSPHATIDYLCHOLINE (DMPC) AND CHOLESTEROL
摘要 An influenza immunizing dosage form comprising a liposome and an antigen of Influenza, particularly the hemagglutinin or bromelain fragment, wherein said liposome and antigen are present in an immunization dose. Additionally, a dosage form, including such form particularly adapted to producing an immune response, comprising a salt form of an organic acid derivative of a sterol and an antigen wherein said organic acid derivative of a sterol and antigen are present in an immunization dose, and method of use. Further, a dosage form, including such form particularly adapted to producing an immune response, comprising dimyristolyphosphatidylcholine (DMPC)/cholesterol liposomes, optionally in an aluminum hydroxide gel, and an antigen wherein said DMPC/cholesterol and antigen are present in an immunization dose, and method of use.
申请公布号 NZ230423(A) 申请公布日期 1993.08.26
申请号 NZ19890230423 申请日期 1989.08.24
申请人 THE LIPOSOME CO INC 发明人 POPESCU, MIRCEA C;ALVING, CARL R;RECINE, MARIE S;ESTIS, LEONARD F;KEYES, LYNN D;JANOFF, ANDREW S
分类号 A61K38/00;A61K9/00;A61K9/127;A61K38/36;A61K39/00;A61K39/12;A61K39/145;B01J13/02 主分类号 A61K38/00
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