THIADIAZINONE.

摘要

Tetrahydroquinolyl- or tetrahydrobenzazepinyl-3,6-dihydro-1,3,4 -thiadiazin-2-ones of formula (I) and their salts are new. In (I) A = -CHR4-CHR5-, -CH2-CR4R5-, -CR4R5-CH2-, -CHR4-CHR5-CH2-, -CHR4-CH2-CHR5-, -CH2-CHR4-CHR5-, -CR4R5-CH2-CH2-, -CH2-CR4R5-CH2- or -CH2CH2-CR4R5-; R1-R5 = H, alkyl, alkenyl or alkynyl; R3 can also be 1-15C acyl; R6 = H, alkyl, alkoxy, OH, F, Cl, Br or I; Z = (H, H), (H, alkyl), (alkyl, alkyl) or O; alkyl, alkenyl, alkynyl and alkoxy gps. have up to 5C; if A = CH2CH2 and Z = O, then one of R1,R2, R3 and R6 must be other than H. Specifically claimed are 5-(1-)3,4-Dimethoxybenzoyl) -1,2,3,4-tetrahydroquinolin-6-yl) -6-methyl-3,6-dihydro-1,3,4-thiadiazin -2-one; and 5-(1-isonicotinoyl-4,4-diethyl -1,2,3,4-tetrahydroquinolin-6-yl) -6-methyl-3,6-dihydro-1,3,4 -thiadiazin-2-one.