| 发明名称 |
MODIFIED HUMAN HEMOGLOBIN, BLOOD SUBSTITUTES CONTAINING THE SAME, AND VECTORS FOR EXPRESSING THE MODIFIED HEMOGLOBIN |
| 摘要 |
The present invention relates to modified beta -chains of human hemoglobin having an oxygen binding affinity equal to or less than natural human hemoglobin. The modified the beta -chain of human hemoglobin of the invention preferably has at least one chloride binding site not present in beta -chain of natural human hemoglobin.
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| 申请公布号 |
US5239061(A) |
申请公布日期 |
1993.08.24 |
| 申请号 |
US19900541011 |
申请日期 |
1990.06.20 |
| 申请人 |
RESEARCH CORPORATION TECHNOLOGIES, INC. |
发明人 |
FRONTICELLI, CLARA;BUCCI, ENRICO;BRINIGAR, WILLIAM |
| 分类号 |
A61K38/00;C07K14/805 |
主分类号 |
A61K38/00 |
| 代理机构 |
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