| 摘要 |
HOE 87/F 370K A process for the preparation of aminoaryl-.beta.-sulfatoethyl-sulfone compounds Aminoaryl-.beta.-sulfatoethylsulfone compounds, such as, for example 4-(.beta.-sulfatoethylsulfonyl)-aniline, can be prepared in a quick and easy manner from their corresponding .beta.-hydroxyethylsulfone compounds by sulfation by spraying a solution or suspension or paste of this aminoaryl-.beta.-hydroxyethylsulfone compound or the acylamino compound thereof in sulfuric acid or aqueous sulfuric acid into a hot inert gas stream of a convection dryer. In this procedure, the drying, esterification reaction and the hydrolysis of any acylamino group present takes place synchronously. The sulfato compound is preferably obtained in the form of granules. |
