| 摘要 |
<p>The invention relates to novel 3-(pyridylamino)-2-(1H^_-tetrazol-5-yl)-acrylnitriles of general formula (I), their geometric isomers, tautomers and hydrates and the preparation thereof. These compounds are useful as favorable starting materials to compounds of general formula (II) which possess first of all antiallergic and antiulcer activity. In general formula (I) R stands for hydrogen, C1-4 alkyl, halogen, hydroxy, nitro, carboxy, C2-5 alkoxycarbonyl or C7-12 aralkoxy; R1 stands for hydrogen, C¿1-4? alkyl or halogen; R?2¿ represents hydrogen, C¿1-4? alkyl or C6-10 aryl. The present invention also relates to a process for the preparation of compounds of general formula (I) and the geometric isomers, tautomers and hydrates thereof.</p> |
