NOVEL ACID ANHYDRIDES AND PREPARATION AND USE THEREOF

摘要

Novel anhydrides of general formula (I), wherein Ar is an aryl radical, and either R1 is C6H5-CO or (CH3)3C-O-CO, R2 is a hydrogen atom and R3 is a hydroxy function protective grouping, or R1 is (CH3)3C-O-CO and R2 and R3 together form a saturated 5 or 6-membered heterocyclic ring; preparation thereof; and uses thereof for preparing taxane derivatives having general formula (III), wherein R = H, acetyl; R1 is C6H5-CO or (CH3)3C-O-CO), and having antitumoral properties.