发明名称 |
TGF-beta induced gene and protein. |
摘要 |
<p>A new TGF- beta induced gene and protein is described. Treatment of TGF- beta growth arrested cells induces the production of a novel gene which encodes a 683 amino acid protein, designated BIG-H3, that contains four homologous repeat regions and which may represent a cell surface recognition molecule. This gene and protein is induced in mammalian cells, and specifically human cells, upon treatment with TGF- beta .</p> |
申请公布号 |
EP0555989(A1) |
申请公布日期 |
1993.08.18 |
申请号 |
EP19930300809 |
申请日期 |
1993.02.04 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
PURCHIO, ANTHONY F.;NEUBAUER, MICHAEL G.;SKONIER, JOHN E. |
分类号 |
C12N15/09;C07K14/00;C07K14/47;C07K14/495;C07K14/52;C07K14/71;C07K16/00;C12N15/12;C12P21/02;C12R1/91 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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