发明名称 Novel pyrrolidine derivatives substituted in the 3-position with a saturated or insaturated fatty acid group, process for their preparation and pharmaceuticals with thromboxane A2 inhibiting activity containing them.
摘要 Compounds of formula (I): <IMAGE> in which: R1 represents: - an optionally substituted alkyl group, - an optionally substituted phenyl group, - a pyridyl group, - an optionally substituted phenylsulphonyl group, - an acyl group, - an optionally substituted benzoyl or pyridylcarbonyl group, - an alkylaminocarbonyl or phenylaminocarbonyl group, - an acylamino or benzoylamino group, R2 represents: - a hydrogen atom, - an optionally substituted phenyl group, - an optionally substituted 3-pyridyl or 2-pyridyl group, R3 represents any one of the following groups: <IMAGE> <IMAGE> - (CH2)n-CO2R in which - m is equal to 2, 3 or 4, - n is equal to 4, 5, 6 or 7, and R represents a hydrogen atom or an alkyl group. Medicaments.
申请公布号 EP0556119(A1) 申请公布日期 1993.08.18
申请号 EP19930400340 申请日期 1993.02.11
申请人 ADIR ET COMPAGNIE 发明人 LAVIELLE, GILBERT;DUBUFFET, THIERRY;MULLER, OLIVIER;LAUBIE, MICHEL;VERBEUREN, TONY
分类号 A61K31/40;A61K31/44;A61K31/4427;A61K31/47;A61P7/02;A61P9/00;A61P9/10;A61P43/00;C07D207/08;C07D207/22;C07D207/48;C07D401/04;C07D401/06;C07D401/12 主分类号 A61K31/40
代理机构 代理人
主权项
地址