| 发明名称 |
Pyridine derivatives and pharmaceutical composition said compound |
| 摘要 |
Pyridine derivatives of formula <CHEM> their heteroaromatic N-oxides and their pharmaceutically acceptable acid addition salts are disclosed. In the formula z is 0,1 and 2 and R,R<1>,R<2> and R<2> have specified meanings. The compounds exhibit activity as 5-HT1A agonists, antagonists or partial agonists and are useful for the treatment of CNS disorders eg anxiety, as antihypertensives and in treating anorexia. |
| 申请公布号 |
PH27590(A) |
申请公布日期 |
1993.08.18 |
| 申请号 |
PH19450000403 |
申请日期 |
1990.04.06 |
| 申请人 |
JOHN WYETH AND BROTHER LIMITED |
发明人 |
IAN ANTHONY CLIFFE;HOWARD LANGHAM MANSELL;RICHARD SIMON TODD;ALAN CHAPMAN WHITE |
| 分类号 |
A61K31/00;A61K31/435;A61K31/47;A61K31/4709;A61K31/473;A61P43/00;C07D215/38;C07D221/04;C07D401/12;C07D401/14;C07D405/12;C07D413/12;C07D417/12;C07D513/04 |
主分类号 |
A61K31/00 |
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