发明名称 Cloning and expression of humanized monoclonal antibodies against human interfluekin-4.
摘要 PCT No. PCT/US93/01301 Sec. 371 Date Aug. 16, 1994 Sec. 102(e) Date Aug. 16, 1994 PCT Filed Feb. 18, 1993 PCT Pub. No. WO93/17106 PCT Pub. Date Sep. 2, 1993Monoclonal antibodies are provided which are specific for human interleukin-4. Also provided are complementary DNAs which encode the heavy and light chain variable regions of such monoclonal antibodies and complementarity determining regions from such DNAs; and kits and methods for detecting, measuring and immunopurifying human interleukin-4, and for blocking the biological activity of human interleukin-4.
申请公布号 ZA9301148(B) 申请公布日期 1993.08.18
申请号 ZA19930001148 申请日期 1993.02.18
申请人 SCHERING CORPORATION 发明人 JOHN S ABRAMS;HUNG V LE;NICHOLAS J MURGOLO;MICHAEL PEARCE;PAUL J ZAVODNY;BARBARA DALIE;KENNETH MILLER;HAHN NGUYEN;STEPHEN TINDALL
分类号 A61K38/00;A61K39/395;A61P43/00;C07K14/47;C07K14/52;C07K14/54;C07K16/00;C07K16/24;C07K16/46;C12N5/10;C12N15/02;C12N15/09;C12N15/13;C12P21/02;C12P21/08;C12R1/91 主分类号 A61K38/00
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