| 摘要 |
<p>An assay for identifying neuro-excitatory agents is provided. The assay comprises suppressing the electrical activity of neuronal cells by incubating the cells in a medium having a reduced concentration of serum. The electrically quiescent cells thus produced are then used to screen candidate materials. Neuro-excitatory agents comprise those materials which are able to restore electrical activity to the quiescent cells. Using the method, a pool of growth factors and a family of insulin-like growth factors have been identified as neuro-excitatory agents.</p> |
