发明名称 |
PREPARATION OF OPTICALLY ACTIVE ALIPHATIC CARBOXYLIC ACIDS |
摘要 |
2128519 9315038 PCTABS00024 An improved process for the separation of enantiomers of a racemic mixture of certain aliphatic carboxylic acids or esters thereof is disclosed. The process involves adding a mixture of the aliphatic carboxylic acid to the material formed by: (i) forming a solution comprising said racemic mixture of a C1 to C6 linear or branched aliphatic carboxylic acid and an organic or inorganic solvent; (ii) treating said solution with a chiral organic nitrogenous base; (iii) precipitating from the reaction solution formed in step (ii) a crystalline material comprised of the less soluble diastereomeric salt. The solution is admixed with the crystalline material for a time sufficient to cause an increase in the amount of the less soluble diastereomeric salt in the crystalline material.
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申请公布号 |
CA2128519(A1) |
申请公布日期 |
1993.08.05 |
申请号 |
CA19922128519 |
申请日期 |
1992.12.16 |
申请人 |
ETHYL CORP |
发明人 |
CHOUDHURY AZFAR A;KADKHODAYAN ABBAS;PATIL DEEPAK R |
分类号 |
C07B57/00;C07C51/487;C07C57/30;C07C67/48;C07C69/65;C07C69/73;(IPC1-7):C07C53/132;C07C67/60 |
主分类号 |
C07B57/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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