| 发明名称 |
PROTECTIVE EFFECTS OF MUTATED SUPERANTIGENS |
| 摘要 |
2128415 9314634 PCTABS00024 The present invention includes a method for preventing or treating the toxic effects of a superantigen. A subject is treated with a molecule which interacts with specific V.beta. elements of T cells in a manner similar to that of a native superantigen. The molecules of the present invention are mutated or modified superantigens which elicit antibody production without inducing T cell proliferation.
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| 申请公布号 |
CA2128415(A1) |
申请公布日期 |
1993.08.05 |
| 申请号 |
CA19932128415 |
申请日期 |
1993.01.28 |
| 申请人 |
NAT JEWISH CT IMMUN & RESPIRAT |
发明人 |
KAPPLER JOHN W;MARRACK PHILIPPA |
| 分类号 |
C12N15/09;A61K39/00;A61P37/00;C07K14/195;C07K14/31;C12N5/10;C12P21/02;(IPC1-7):C07K14/31 |
主分类号 |
C12N15/09 |
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