发明名称 Difluoromethylenandrostenone derivatives and process for their preparation
摘要 The invention relates to new 6-difluoromethylenandrostenones having formula (I) wherein the symbol - &cir& _- &cir& _- &cir& _ represents a double or single bond; R is hydrogen or C1-C4 alkyl; and A is a =C=O, =CH <SIGN> OH or =CH <SIGN> OR1 group, in which R1 is an acyl group, which are useful as steroidal aromatase inhibitors.
申请公布号 ZA9300035(B) 申请公布日期 1993.08.05
申请号 ZA19930000035 申请日期 1993.01.05
申请人 FARMITALIA CARLO ERBA S.R.L. 发明人 FRANCO BUZETTI;ANTONIO LONGO;ANGELO CRUGNOLA;ENRICO DI SALLE
分类号 A61K31/565;C07J1/00;C07J71/00;C12N9/99 主分类号 A61K31/565
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