发明名称 PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES
摘要 The present invention relates to N-pyridylamidine and N-pyridylguanidine derivatives of general formula (I) in which: Ar<1> is an optionally substituted phenyl ring; Ar<2> is an optionally substituted phenyl ring; R<1> is hydrogen or C1-4alkyl; R<2> is hydrogen or C1-4alkyl; R<3> is hydrogen or C1-4alkyl; R<4> is hydrogen, halogen, C1-6alkyl or C1-6alkoxy; X is CH2 or NR<5>, and R<5> is hydrogen or C1-4alkyl, and the salts thereof, and their use in therapy as gastric acid secretion inhibitors.
申请公布号 WO9315055(A1) 申请公布日期 1993.08.05
申请号 WO1993EP00174 申请日期 1993.01.26
申请人 SMITHKLINE BEECHAM INTERCREDIT B.V. 发明人 IFE, ROBERT, JOHN;LEACH, COLIN, ANDREW;DHANAK, DASHYANT
分类号 A61K31/44;A61K31/4418;A61P1/04;C07D213/75 主分类号 A61K31/44
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