发明名称 |
PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES |
摘要 |
The present invention relates to N-pyridylamidine and N-pyridylguanidine derivatives of general formula (I) in which: Ar<1> is an optionally substituted phenyl ring; Ar<2> is an optionally substituted phenyl ring; R<1> is hydrogen or C1-4alkyl; R<2> is hydrogen or C1-4alkyl; R<3> is hydrogen or C1-4alkyl; R<4> is hydrogen, halogen, C1-6alkyl or C1-6alkoxy; X is CH2 or NR<5>, and R<5> is hydrogen or C1-4alkyl, and the salts thereof, and their use in therapy as gastric acid secretion inhibitors. |
申请公布号 |
WO9315055(A1) |
申请公布日期 |
1993.08.05 |
申请号 |
WO1993EP00174 |
申请日期 |
1993.01.26 |
申请人 |
SMITHKLINE BEECHAM INTERCREDIT B.V. |
发明人 |
IFE, ROBERT, JOHN;LEACH, COLIN, ANDREW;DHANAK, DASHYANT |
分类号 |
A61K31/44;A61K31/4418;A61P1/04;C07D213/75 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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